Visceral Leishmaniasis with Generalized Involvement of Lymph Nodes in a 55-Year-Old Woman: A Case Report

A 55-year-old woman was presented with fever, splenomegaly, generalized lymphadenopathy and weight loss. The patient came from Sreepur, an endemic region of Kala-azar in Bangladesh. About 2 years back, the patient presented with fever and splenomegaly and on investigation, ICT for Kala-azar was found positive. Thus the patient was diagnosed as a case of visceral Leishmaniasis and was treated with Miltefosin in full dosage form. The condition was improved with the treatment. After about a year of treatment the patient again developed fever and splenomegaly; this time was also generalized lymphadenopathy. Lymph node biopsy showed non-Hodgkin’s lymphoma and bone marrow study showed the presence of LD-bodies. FNAC from cervical and epitrochlear lymph nodes showed the presence of LD bodies without the presence of any malignant cells, so she was diagnosed as a case of treatment failure of visceral Leishmaniasis with lymphatic involvement. [J Sci Found, 2012;10(2):80-84]